Survival benefit of solid-organ transplant in the United States.
JAMA Surg. 2015; 150: 252-259
Chronic lung allograft dysfunction: definition, diagnostic criteria, and approaches to treatment-a consensus report from the Pulmonary Council of the ISHLT.
J Heart Lung Transplant. 2019; 38: 493-503
An international ISHLT/ATS/ERS clinical practice guideline: diagnosis and management of bronchiolitis obliterans syndrome.
Eur Respir J. 2014; 44: 1479-1503
The microbiome and the respiratory tract.
Annu Rev Physiol. 2016; 78: 481-504
Bacterial topography of the healthy human lower respiratory tract.
MBio. 2017; 8: e02287-e02316
Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype.
Nat Microbiol. 2016; 116031
Severity-related changes of bronchial microbiome in chronic obstructive pulmonary disease.
J Clin Microbiol. 2014; 52: 4217-4223
Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome.
Nat Microbiol. 2016; 116113
Lung dysbiosis, inflammation, and injury in hematopoietic cell transplantation.
Am J Respir Crit Care Med. 2018; 198: 1312-1321
The role of bacteria in the pathogenesis and progression of idiopathic pulmonary fibrosis.
Am J Respir Crit Care Med. 2014; 190: 906-913
Lung microbiota contribute to pulmonary inflammation and disease progression in pulmonary fibrosis.
Am J Respir Crit Care Med. 2019; 199: 1127-1138
Lung microbiota predict clinical outcomes in critically ill patients.
Am J Respir Crit Care Med. 2020; 201: 555-563
Sputum microbiome is associated with 1-year mortality after chronic obstructive pulmonary disease hospitalizations.
Am J Respir Crit Care Med. 2019; 199: 1205-1213
A novel microbiota stratification system predicts future exacerbations in bronchiectasis.
Ann Am Thorac Soc. 2014; 11: 496-503
Maturation of the infant respiratory microbiota, environmental drivers, and health consequences. a prospective cohort study.
Am J Respir Crit Care Med. 2017; 196: 1582-1590
The lung microbiome and transplantation.
Curr Opin Organ Transplant. 2019; 24: 305-310
Lung-enriched organisms and aberrant bacterial and fungal respiratory microbiota after lung transplant.
Am J Respir Crit Care Med. 2012; 186: 536-545
Changes in the lung microbiome following lung transplantation include the emergence of two distinct Pseudomonas species with distinct clinical associations.
PLoS One. 2014; 9e97214
Candida albicans and bacterial microbiota interactions in the cecum during recolonization following broad-spectrum antibiotic therapy.
Infect Immun. 2012; 80: 3371-3380
Development of a dual-index sequencing strategy and curation pipeline for analyzing amplicon sequence data on the MiSeq Illumina sequencing platform.
Appl Environ Microbiol. 2013; 79: 5112-5120
Reagent and laboratory contamination can critically impact sequence-based microbiome analyses.
BMC Biol. 2014; 12: 87
Standardisation of spirometry.
Eur Respir J. 2005; 26: 319-338
Bacterial burden in the lower airways predicts disease progression in idiopathic pulmonary fibrosis and is independent of radiological disease extent.
Eur Respir J. 2020; 551901519
Lung microbiota contribute to pulmonary inflammation and disease progression in pulmonary fibrosis.
Am J Respir Crit Care Med. 2019; 199: 1127-1138
Impact of immediate primary lung allograft dysfunction on bronchiolitis obliterans syndrome.
Am J Respir Crit Care Med. 2007; 175: 507-513
Report of the ISHLT Working Group on Primary Lung Graft Dysfunction, part I: definition and grading—a 2016 consensus group statement of the International Society for Heart and Lung Transplantation.
J Heart Lung Transplant. 2017; 36: 1097-1103
Acute cellular rejection is a risk factor for bronchiolitis obliterans syndrome independent of post-transplant baseline FEV1.
J Heart Lung Transplant. 2009; 28: 888-893
Introducing mothur: open-source, platform-independent, community-supported software for describing and comparing microbial communities.
Appl Environ Microbiol. 2009; 75: 7537-7541
vegan: Community Ecology Package.
mvabund-an R package for model-based analysis of multivariate abundance data.
Methods Ecol Evol. 2012; 3: 471-474
A class of rank test procedures for censored survival data.
Biometrika. 1982; 69: 553-566
Contributions to the theory of rank order statistics-the two-sample case.
Ann Math Statist. 1956; 27: 590-615
Nonparametric estimation from incomplete observations.
J Am Stat Assoc. 1958; 53: 457-481
Regression models and life-tables.
J R Stat Soc B. 1972; 34: 187-202
Enrichment of lung microbiome with supraglottic taxa is associated with increased pulmonary inflammation.
Microbiome. 2013; 1: 19
Laboratory contamination over time during low-biomass sample analysis.
Mol Ecol Resour. 2019; 19: 982-996
Severity of lymphocytic bronchiolitis predicts long-term outcome after lung transplantation.
Am J Respir Crit Care Med. 2008; 177: 1033-1040
De novo DQ donor-specific antibodies are associated with chronic lung allograft dysfunction after lung transplantation.
Am J Respir Crit Care Med. 2016; 194: 596-606
De novo donor HLA-specific antibodies predict development of bronchiolitis obliterans syndrome after lung transplantation.
J Heart Lung Transplant. 2014; 33: 1273-1281
Cytomegalovirus replication within the lung allograft is associated with bronchiolitis obliterans syndrome.
Am J Transplant. 2011; 11: 2190-2196
Cytomegalovirus pneumonitis is a risk for bronchiolitis obliterans syndrome in lung transplantation.
Am J Respir Crit Care Med. 2010; 181: 1391-1396
Respiratory viral infections are a distinct risk for bronchiolitis obliterans syndrome and death.
Am J Respir Crit Care Med. 2004; 170: 181-187
Pseudomonal airway colonisation: risk factor for bronchiolitis obliterans syndrome after lung transplantation?.
Eur Respir J. 2008; 31: 1037-1045
Pseudomonas aeruginosa colonization of the allograft after lung transplantation and the risk of bronchiolitis obliterans syndrome.
Transplantation. 2008; 85: 771-774
Impact of graft colonization with gram-negative bacteria after lung transplantation on the development of bronchiolitis obliterans syndrome in recipients with cystic fibrosis.
Respir Med. 2009; 103: 743-749
Interaction between Pseudomonas and CXC chemokines increases risk of bronchiolitis obliterans syndrome and death in lung transplantation.
Am J Respir Crit Care Med. 2013; 187: 518-526
Role of C1q-binding anti-HLA antibodies as a predictor of lung allograft outcome.
Eur Respir J. 2018; 521701898
CXCR3 chemokine ligands during respiratory viral infections predict lung allograft dysfunction.
Am J Transplant. 2012; 12: 477-484
The lung microbiota of healthy mice are highly variable, cluster by environment, and reflect variation in baseline lung innate immunity.
Am J Respir Crit Care Med. 2018; 198: 497-508
Lung and gut microbiota are altered by hyperoxia and contribute to oxygen-induced lung injury in mice.
Sci Transl Med. 2020; 12eaau9959
Bronchiolitis obliterans syndrome susceptibility and the pulmonary microbiome.
J Heart Lung Transplant. 2018; 37: 1131-1140
Influence of azithromycin and allograft rejection on the post-lung transplant microbiota.
J Heart Lung Transplant. 2020; 39: 176-183
Reestablishment of recipient-associated microbiota in the lung allograft is linked to reduced risk of bronchiolitis obliterans syndrome.
Am J Respir Crit Care Med. 2013; 187: 640-647
Distal airway microbiome is associated with immunoregulatory myeloid cell responses in lung transplant recipients.
J Heart Lung Transplant. 2017; 37: 206-216
Airway microbiota determines innate cell inflammatory or tissue remodeling profiles in lung transplantation.
Am J Respir Crit Care Med. 2016; 194: 1252-1263
Airway microbiota signals anabolic and catabolic remodeling in the transplanted lung.
J Allergy Clin Immunol. 2018; 141 (): 718
Cell-associated bacteria in the human lung microbiome.
Microbiome. 2014; 2: 28
Changes in the lung microbiome following lung transplantation include the emergence of two distinct Pseudomonas species with distinct clinical associations.
PLoS One. 2014; 9e97214
Impact of gram negative bacteria airway recolonization on the occurrence of chronic lung allograft dysfunction after lung transplantation in a population of cystic fibrosis patients.
BMC Microbiol. 2018; 18: 88
The potential impact of azithromycin in idiopathic pulmonary fibrosis.
Eur Respir J. 2019; 531800628
Treating idiopathic pulmonary fibrosis with the addition of co-trimoxazole: a randomised controlled trial.
Thorax. 2013; 68: 155-162
Randomised, double-blind, placebo-controlled trial with azithromycin selects for anti-inflammatory microbial metabolites in the emphysematous lung.
Thorax. 2017; 72: 13-22
Long-term azithromycin therapy for bronchiolitis obliterans syndrome: divide and conquer?.
J Heart Lung Transplant. 2010; 29: 1358-1368
Airway bacterial load and inhaled antibiotic response in bronchiectasis.
Am J Respir Crit Care Med. 2019; 200: 33-41
Mycophenolate mofetil reduces alveolar inflammation, acute rejection and graft loss due to bronchiolitis obliterans syndrome after lung transplantation.
Pulm Pharmacol Ther. 2010; 23: 445-449
Mycophenolate mofetil versus azathioprine immunosuppressive regimens after lung transplantation: preliminary experience.
J Heart Lung Transplant. 1998; 17: 768-774
Mycophenolic acid versus azathioprine as primary immunosuppression for kidney transplant recipients.
Cochrane Database Syst Rev. 2015; 12CD007746
Comparison of mycophenolate mofetil and azathioprine for prevention of bronchiolitis obliterans syndrome in de novo lung transplant recipients.
Transplantation. 2006; 81: 998-1003
