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ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunity

researchsnappy by researchsnappy
February 19, 2020
in Healthcare Research
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ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunity
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Competing interests

V.P.B. is a recipient of an immuno-oncology translational research grant from Bristol-Myers Squibb and is an inventor on a patent application related to work on neoantigen modelling. S.D.L. is a member of the scientific advisory board of Nybo Pharmaceuticals, and co-founder of Episteme Prognostics. J.D.W. is a consultant for Adaptive Biotech, Advaxis, Amgen, Apricity, Array BioPharma, Ascentage Pharma, Astellas, Bayer, Beigene, Bristol-Myers Squibb, Celgene, Chugai, Elucida, Eli Lilly, F Star, Genentech, Imvaq, Janssen, Kleo Pharma, Linneaus, MedImmune, Merck, Neon Therapuetics, Ono, Polaris Pharma, Polynoma, Psioxus, Puretech, Recepta, Trieza, Sellas Life Sciences, Serametrix, Surface Oncology and Syndax; is a recipient of research support from Bristol-Myers Squibb, Medimmune, Merck Pharmaceuticals and Genentech; has equity in Potenza Therapeutics, Tizona Pharmaceuticals, Adaptive Biotechnologies, Elucida, Imvaq, Beigene, Trieza and Linneaus; and has received an honorarium from Esanex. T.M. is a consultant for Immunos Therapeutics and Pfizer; is a co-founder with equity in Imvaq Therapeutics; receives research funding from Bristol-Myers Squibb, Surface Oncology, Kyn Therapeutics, Infinity Pharmaceuticals Inc., Peregrine Pharmaceuticals Inc., Adaptive Biotechnologies, Leap Therapeutics Inc. and Aprea; and is an inventor on patent applications related to work on Oncolytic Viral Therapy, Alpha Virus Based Vaccine, Neo Antigen Modeling, CD40, GITR, OX40, PD-1 and CTLA-4. M. Gururajan is an employee of Bristol-Myers Squibb and has financial interest in the company.

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